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GNomEx — Genomic Experiment Repository & LIMS

Molecular Data Repository & Experimental Data Management for Genomic Analysis

University of Utah Huntsman Cancer Institute CODE • Comprehensive Oncology Data & Engineering • Cancer Center Shared Resource

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GNomEx application screenshot

GNomEx is a software solution developed by the Huntsman Cancer Institute's (HCI) Comprehensive Oncology Data & Engineering (CODE). It documents, organizes, and tracks data produced by the High-Throughput Genomics and Cancer BioInformatics (CBI) Shared Resources.

GNomEx serves as a data repository for genomic experiments and analyses. It also serves as a laboratory information management system (LIMS) that records information at all steps of the experimental process.

Through GNomEx, researchers can submit experiment requests electronically, check the status of pending experiments, and collect results for both raw and analyzed data files.

In addition to capturing experiment requests, researchers can organize experiments within project folders, and they can create and search structured annotations on projects, experiments, and their samples.

GNomEx helps manage experiments as they are performed in the laboratory. It tracks experimental parameters at every workflow step, documents protocols associated with experimental handling of the samples, registers barcodes for the tracking of sequencing data and flowcells, and manages billing.


Key Capabilities

CONFIGURATION GNomEx has unlimited configuration options. Users have complete control of what data should be collected for an experiment or analysis. New experiment platforms can be defined as new sequencing hardware becomes available. Multiple cores can be defined to support different sequencing centers.

COLLABORATION GNomEx documents, organizes, and tracks high-throughput next-generation sequencing experiments performed by the High-Throughput Genomics and Cancer BioInformatics (CBI) Shared Resources.

INTEGRATION If provided sample identifiers, will link to CORE system for specimen details. Via CORE, other HCI databases (CCR, RSR, Tumor Registry, Molecular Profiling) provides access to critical data from research and clinical systems.

REPORTING Experiment results and downstream analyses can be downloaded as individual files or at the folder level. Guest users can browse experiments and download data that has been made publicly available.

SECURITY Safeguards experiment annotations and data files so that only permitted researchers are allowed access. Investigators can broaden access to an experiment in order to share it with outside collaborators or make it publicly available.


GNomEx Features

GNomEx documents, organizes, and tracks experiments performed by the High-Throughput Genomics and Cancer BioInformatics (CBI) Shared Resources.

EXPERIMENT ORDERING — A wizard-like interface walks the researcher through the steps of ordering an experiment (submitting a request). Automatic email functionality keeps the researcher informed on sample quality and experiment status.

EXPERIMENT ANNOTATION — Supports annotating experiments with the experiment design and sample characteristics.

EXPERIMENT BROWSING AND SEARCHING — Organizes experiments within project folders. Supports browsing by experiment platform, date, and name of the researcher or lab group. Allows performing simple text searches as well as advanced, criteria-based searches on experiments and associated analyses.

SERVING EXPERIMENTAL RESULTS AND ANALYSIS DATA FILES — Allows downloading experiment results and downstream analyses as individual files or at the folder level.

PUBLIC EXPERIMENT REPOSITORY — Guest users can browse experiments and download data that the researcher has made publicly available.

LABORATORY WORKFLOW — Supports tracking experiment progress via a workflow and each lab step involved in the sequencing. Provides screens for managing and documenting laboratory protocols associated with experimental processes.

BILLING — Generates charges based on structured pricing sheets that the core facility reviews and approves. Automatically emails each lab's billing contact an invoice of the services performed during the month. GNomEx interfaces with the University general ledger system for electronic billing.


Requirements

  • Google Chrome (latest)
  • Microsoft Edge (latest)
  • Safari (latest)

Services Available

  • Training
  • Technical Support
  • Application Configuration
  • Application Development
  • Query and Report Generation
  • Natural Language Processing

CODE Open Office Hours

Held Virtually 1-2 pm every Thursday.
Must Join via the Teams application (not through a browser).
Click Join Teams Meeting

Contact Us

CODE Shared Resource
Director

Andrew Post, MD, PhD
Andrew.Post@hci.utah.edu
801-585-0600

CODE Shared Resource
Associate Director

Shirleen Hewitt, DBA, MBA, MS
Shirleen.Hewitt@hci.utah.edu
801-585-5972

Governance

HCI Senior Director Oversight
Aik Choon Tan, PhD

Shared Resource Advisory
Committee Chair

Howard Colman, MD, PhD

Shared Resource Advisory
Committee Members

Shannon Buckley, PhD
Nicola Camp, PhD
Christopher Fillmore, PhD
Anne Kirchhoff, PhD, MPH
Jessica Moehle, CCRP
Mark Oberg
Melanie Ward